Table 3 Physicochemical characterization of NLCs (mean ± S.D., n = 3).

From: Potential advantages of a novel chitosan-N-acetylcysteine surface modified nanostructured lipid carrier on the performance of ophthalmic delivery of curcumin

Responses

NLC

CH-NLC

CS-NACH-NLC

CS-NACM-NLC

CS-NACL-NLC

PS (nm)

50.76 ± 2.21

93.04 ± 1.87 a

88.64 ± 1.25 a , b

71.52 ± 1.43 a , c

70.25 ± 1.81 a , c

PI

0.11 ± 0.02

0.28 ± 0.05 a

0.17 ± 0.01 a , b

0.16 ± 0.02 a , b

0.16 ± 0.02 a , b

ZP (mV)

−20.38 ± 0.39

30.23 ± 0.25 a

22.51 ± 0.34 a , b

14.62 ± 0.64 a , b , c

11.73 ± 0.27 a , b , c

EE (%)

90.06 ± 1.82

90.49 ± 3.21 a

96.62 ± 3.13 a , b

95.33 ± 2.25 a , b

95.02 ± 0.81 a , b

  1. aStatistically significant compared with the NLC (p < 0.05).
  2. bStatistically significant compared with the CH-NLC (p < 0.05).
  3. cStatistically significant compared with the CS-NACH-NLC (p < 0.05).