Figure 4
From: Loss of tumorigenic potential upon transdifferentiation from keratinocytic into melanocytic lineage
Methylation array analysis.
(A) Methylation array SNP analysis. MET-4 and MT-MET-4 cells show extremely similar SNP profiles confirming that MT-MET-4 are indeed derived from MET-4 cells. (B) Dendrogram of methylation array analysis. All three MET-4 samples cluster together and all three MT-MET-4 samples cluster together. (C) Global DNA methylation. A higher overall methylation was found in MT-MET-4 cells compared to MET-4 throughout the genome.
