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Figure 1

From: Long Non-coding RNA H19 Inhibits Adipocyte Differentiation of Bone Marrow Mesenchymal Stem Cells through Epigenetic Modulation of Histone Deacetylases

Figure 1

Expression profiles of lncRNA H19 and H19-derived miR-675 during adipogenic differentiation of BMSCs.

(A) Left: relative expression of H19 during differentiation as determined by qRT-PCR analysis. Right: relative miR-675 transcript levels at the indicated time points during differentiation. (B) Relative mRNA expression levels of the adipogenic markers PPARγ, C/EBPα and FABP4 at the indicated time points, as in (A). RNA expression at the time points was normalized to that on day 0. (C) Western blot analysis (left) and quantification (right) of protein expression of PPARγ, C/EBPα, FABP4 and the internal control GAPDH at the indicated time points, as in (A). Results are presented as mean ± SD (*P < 0.05, **P < 0.01 compared to BMSCs without adipocyte induction).

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