Figure 1

GTP binding motifs and phylogenetic analysis of BmAtlastin-n.
(A) Conserved sequences of GTP binding motifs of Atlastins and GBPs. The Atlastin sequences shown are protein sequences of specific species, Bombyx mori, Homo sapiens, Mus musculus, Xenopus tropicalis and Drosophila melanogaster. The GBP protein sequences of Homo sapiens, Mus musculus, Xenopus laevis and Danio rerio are shown. Each sequences had four GTP-binding domains and two switch regions. The conserved key residues are shown in green and the conserved variable residues in yellow. (B) Bayesian phylogenetic tree of dynamin superfamily. The dynamin superfamily includes dynamins (red), dynamin-like proteins (DLP, gray), optic atrophy 1 (OPA1, orange), Mx proteins (green), Mitofusins (purple), guanylate binding proteins (GBPs, blue) and Atlastins (yellow).