Figure 5: Enhancement of sEPSCs of neurons by capsaicin in control rats.

(a) Representative traces illustrating sEPSCs before and after the addition of capsaicin (CAP, 5 μM). (b) Cumulative fraction of interevent intervals of sEPSCs in one BLA pyramidal neuron under the pre-drug and post-drug conditions (left); bar plot showing the significant increase in sEPSC frequency by CAP (right); frequency of CAP-treated neurons was normalized by that from the same neuron before CAP-treatment. (c) Cumulative fraction of peak amplitude of sEPSCs under the pre-drug and post-drug conditions (left); bar plot showing the significant increase of sEPSC amplitude by CAP (right); amplitude of CAP-treated neurons was normalized by that from the same neuron before CAP-treatment. (d) Representative traces illustrating mEPSCs before and after the addition of CAP at 5 μM; Na⁺ channel blocker TTX (1 μM) was used to block action potentials. (e) Cumulative fraction of interevent intervals of mEPSCs in one BLA pyramidal neuron under the pre-drug and post-drug conditions (left); bar plot showing the significant increase of mEPSC frequency by CAP (right); frequency of CAP-treated neurons was normalized by that from the same neuron before CAP-treatment. (f) Cumulative fraction of peak amplitude of mEPSCs under the pre-drug and post-drug conditions (left); bar plot showing that mEPSC amplitude was unaffected by CAP-treatment (right); amplitude of CAP-treated neuron was normalized by that from the same neuron before CAP-treatment. *P < 0.05 vs. Pre.