Figure 6: Capsaicin did not affect sIPSCs in BLA neurons of control rats.

(a) Representative traces illustrating sIPSCs were eliminated after the addition of picrotoxin (PTX, 100 μM) and CGP52432 (2 μM). Applications of glutamatergic receptor antagonists CNQX (10 μM) and D-AP5 (30 μM) were used in the external solution to block excitatory synaptic transmission. (b) Recordings illustrating sIPSCs before and after the addition of CAP (5 μM). (c) Cumulative fraction of interevent intervals of sIPSCs in one BLA neuron under the pre-drug and post-drug conditions (left); bar plot showing that frequency of sIPSCs was not altered by CAP (right); frequency of CAP-treated neurons was normalized by that from the same neuron before CAP-treatment. (d) Cumulative fraction of peak amplitude of sIPSCs under the pre-drug and post-drug conditions (left); bar plot showing that amplitude of sIPSCs was not changed by CAP (right); amplitude of CAP-treated neuron was normalized by that from the same neuron before CAP-treatment.