Figure 5: Comparing the ratio of toxic Aβ42 conformer to total Aβ42 in CSF between AD/MCI patients and age-matched individuals by sandwich ELISA.

ELISA detection results: (a) ratio of toxic conformer of Aβ42 to total Aβ42, (b) toxic conformer of Aβ42, and (c) total Aβ42 in CSF of AD/MCI patients (n = 13) and age-matched controls (n = 12).