Figure 6
Comparison of OLED POC assay to Rapid ELISA laboratory test for multiplexed detection of human IgG in patient sera.
Sera from 29 HPV16+ patients and 39 healthy controls were evaluated for the detection of HPV16 E2 and E7 specific IgG. The results of the (a) OLED-based point-of-care test configuration against our previously reported (b) RAPID ELISA assay are shown. OLED-based configuration demonstrated sensitivity of 59% at 95% specificity using a cutoff value of the mean of the controls +2 standard deviations compared to our previously reported RAPID ELISA laboratory test instrumentation with a sensitivity of 83% at 95% specificity. Significance was determined using a student’s t-test.
