Figure 4: Correlation scatter plots of the expression levels of 370 genes among more than thirteen pathways in the liver and spleen tissues of the normal and cirrhosis group post the SPION injection versus the controls by RT2 PCR array analysis. | Scientific Reports

Figure 4: Correlation scatter plots of the expression levels of 370 genes among more than thirteen pathways in the liver and spleen tissues of the normal and cirrhosis group post the SPION injection versus the controls by RT2 PCR array analysis.

From: Iron overload by Superparamagnetic Iron Oxide Nanoparticles is a High Risk Factor in Cirrhosis by a Systems Toxicology Assessment

Figure 4

The gene levels of each sample were first normalized with four internal housekeeping genes and then plotted according to the expression levels in the SPION group versus those of the control. Genes with more than 2-folds regulation were considered significant with the red dots for the upregulated and the blue ones for the down-regulated. The dash lines indicated the range of 2-folds changes. The data presented were from the results of RT2 PCR array analysis of two independent tissue samples in each group.

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