Figure 8
From: Early hippocampal volume loss as a marker of eventual memory deficits caused by repeated stress
Summary of the different temporal development of structural and behavioral deficits caused by chronic stress.
Stress causes a loss in total hippocampal volume as early as day3, which progresses with the 10-day chronic stress. The right hippocampal volume loss is evident only after chronic stress, but the left hippocampal volume loss is evident as early as day3 and progresses with the 10-day chronic stress paradigm. The spatial memory impairment caused by stress also varies over time. A trend of deficit in spatial memory was observed on day5 in Morris water maze task, however the same animals show a strong deficit in spatial memory on day13 observed in object displacement task.
