Figure 7

Structural comparison of residues for binding of mannose in CGL1 and other mannose-binding lectins.
Stick models for the interactions of mannose with CGL1(A), α-Me-Mannoside with MBP-A from rat serum (B), binding model of CGL1 and mannobiose (C) and Dln1and mannobiose (D). Ca2+ ions are indicated in gray spheres. Mannose, the mannose-derivative and the residues are shown as stick figures. The dotted lines denote hydrogen bonds. Residues without dotted lines have hydrophobic interactions with the sugars.