Table 3 Variability analysis on histogram metrics of pharmacokinetic parameters of DCE-MRI.

From: Dynamic Contrast-enhanced MR Imaging in Renal Cell Carcinoma: Reproducibility of Histogram Analysis on Pharmacokinetic Parameters

Kinetic Parameters

Histogram Metrics

Coefficient of variation (%)

Intra-observer

Inter-observer

Scan-rescan

K trans

Mean

0.98

2.31

10.82

Mode

2.10

10.54

25.44

Skewness

0.73

23.84

32.29

Kurtosis

42.22

66.72

85.84

V e

Mean

0.72

1.84

6.88

Mode

0.66

9.21

15.43

Skewness

47.87

114.86

109.42

Kurtosis

40.92

87.36

40.53

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