Figure 4: Inhibition by MNQO of tripartite complex proteins that mediate melanosome transport. | Scientific Reports

Figure 4: Inhibition by MNQO of tripartite complex proteins that mediate melanosome transport.

From: Inhibitory effect of 2-methyl-naphtho[1,2,3-de]quinolin-8-one on melanosome transport and skin pigmentation

Figure 4

Levels of Rab27a, Mlph and MyoVa (A) and MITF proteins (B) were measured in melanocytes by western blotting. The melan-a melanocytes were treated with 2 μM, 10 μM and 20 μM MNQO, or with 0.1% DMSO for 72 h. (C) Quantification of Rab27a, Mlph, MyoVa and MITF protein expression level. Values are mean value of expression normalized to β-actin from three independent experiments ± SD.

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