Figure 2: Somatic copy number analysis of chromosome 3 in four tumors.
From: Independent Tumor Origin in Two Cases of Synchronous Bilateral Clear Cell Renal Cell Carcinoma

(A) Copy number profiles of chromosome 3 of four tumors. (B,C) Focal copy number profiles covering ccRCC driver genes on chromosome 3p. Y-axis is log2R, and the X-axis represents position along chromosome 3 in hg19. X indicates the approximate position of the centromere. Redlines, the average Log2R of variant alleles calculated using a circular binary segment (CBS) algorism, are indicative of the copy numbers of the corresponding chromosomal segments.