Figure 4 | Scientific Reports

Figure 4

From: Nucleotide-binding oligomerization domain-containing protein 2 prompts potent inflammatory stimuli during Neospora caninum infection

Figure 4

The presence of functional Nod2 increases lethality induced by N. caninum infection.

Nod2−/− and WT mice were infected with different doses of N. caninum tachyzoites, able to kill ~50% (LD50, n = 8 mice per group; (A)) or 100% (LD100, n = 5 mice per group; (B)) of the mice and the survival was evaluated for 40 and 30 days, respectively. Differences in survival rates between groups were compared using Kaplan-Meier survival analysis, through a log-rank Mantel-Cox test. Data are representative of three independent experiments. *Statistical difference (*P ≤ 0.05) between WT and Nod2−/− mice.

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