Figure 6 | Scientific Reports

Figure 6

From: Multi-functionality Redefined with Colloidal Carotene Carbon Nanoparticles for Synchronized Chemical Imaging, Enriched Cellular Uptake and Therapy

Figure 6

In vitro cellular studies.

MTT assay for the evaluation of cytotoxic effects of β-carotene in free or passivated to CNPs with post coatings of amphiphilic phospholipidic assembly. Experiment was performed in (A,C) MDA-MB231 breast cancer and (B,D) C32 melanoma cells after incubation for (A,B) 48 and (C,D) 72 h at various concentrations (125, 62.5, 31.25, 15.6125, 7. 8 and 3.9 μM) of β-carotene in free or form of C3 nanoparticles and C3-Lipocoat nanoparticle formulations. (E) Comparative IC50 values of used formulations and (F) fold change across both the cell lines. Statistical analysis performed using Two-way ANOVA on IC50 values represented as *** for p < 0.001.

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