Figure 4: LysGH15 protected the mice from lethal MRSA infection. | Scientific Reports

Figure 4: LysGH15 protected the mice from lethal MRSA infection.

From: LysGH15 kills Staphylococcus aureus without being affected by the humoral immune response or inducing inflammation

Figure 4

(A) The rescue of mice from lethal MRSA (YB57) infection using LysGH15. BALB/c mice immunized with lysin or control buffer were challenged intravenously with YB57 MRSA (1 × 1010 CFU/mouse). One hour later, 50 μg of LysGH15 or control buffer was injected into the mice. (B) Colony counts in peripheral blood samples. At the indicated times, the bacterial counts (CFU/mL) in the mice were determined from peripheral blood samples (10 μL) obtained from the caudal vein (n = 6 mice per group per experiment). *P < 0.05 compared with the buffer-treated control. The data are representative of 3 experiments.

Back to article page