Figure 6: LysGH15 did not cause significant adverse effects. | Scientific Reports

Figure 6: LysGH15 did not cause significant adverse effects.

From: LysGH15 kills Staphylococcus aureus without being affected by the humoral immune response or inducing inflammation

Figure 6

The mice were immunized with LysGH15 at 3 weeks prior to the intravenous administration of large amounts of LysGH15 or buffer. The mice were monitored for 10 days and euthanized on day 11. (A) The health score was assessed as described in the Methods section. (B) Pathological changes and histopathology of the organs. The hearts, livers, spleens, lungs, kidneys, and colons were stained with haematoxylin and eosin. n = 6 mice per group per experiment. *P < 0.05 compared to the buffer-treated control; N.S. not significant. The data are representative of three experiments.

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