Figure 3: Knockdown of PTX3 induces cell cycle arrest G2/M phase of SiHa and HeLa cells.
From: Knockdown of Pentraxin 3 suppresses tumorigenicity and metastasis of human cervical cancer cells

(a) Flow cytometry analysis of knockdown PTX3 in SiHa and HeLa cells. Right panel shows quantification of cell cycle distribution. (b) Western blotting analysis of PTX3, cyclin B1, p-cdc2, cdc2, p-cdc25c, cdc25c, p21, and p27 protein in knockdown PTX3 cells. β-actin served as the loading control. Right panel shows quantification of protein expression. The data represent the mean ± SE of three different experiments. **P < 0.01.