Figure 1
From: Efficient Inhibition of Hepatitis B Virus Infection by a preS1-binding Peptide
B10 concatemers exhibited increased preS1- and HBV-binding activities.
(A) Schematic representation of B10 concatemers. B10 monomers were depicted as dark gray boxes (left) and in boldface letters (right). Terminal protective residues and internal tri-peptide spacers (SP) were italicized. (B) B10 concatemers exhibit an increased activity in binding to preS1/2-48myr. FITC-labelled preS1/2-48myr captured by the immobilized N-biotinylated B10 monomer or concatemer was quantified via fluorescence measurment. (C) B10 concatemers exhibit an increased activity in binding to HBV. Captured HBV particles were detected with HRP-conjugated polyclonal anti-HBsAg antibody. *p < 0.05; **p < 0.01; ***p < 0.001; ns, not significant.
