Table 2 The extent of activation in vivo of the progeny viruses in lung lavage fluids of mice infected with MA-B/Ibaraki/85[V].

From: TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus

 

Titre (PFU/ml)

Mouse

n = 3

Trypsin+

Trypsin−

Activation (%) a

2 days p.i.

WT

Means

7.2 × 106

6.8 × 106

94.4

 

SD

3.3 × 106

1.9 × 106

 

KO

Means

3.2 × 106

4.7 × 106

146.9

 

SD

1.3 × 106

0.3 × 106

 

4 days p.i.

WT

Means

5.7 × 106

1.3 × 106

22.8

 

SD

1.9 × 106

0.3 × 106

 

KO

Means

1.7 × 106

7.7 × 105

45.3

 

SD

1.6 × 106

6.5 × 105

 

6 days p.i.

WT

Means

2.4 × 106

7.2 × 105

30.0

 

SD

2.3 × 106

2.8 × 105

 

KO

Means

2.9 × 105

1.9 × 105

65.5

 

SD

3.1 × 105

1.5 × 105

 
  1. aThe percentage of virus titres activated in vivo (Trypsin−) in total virus titres activated ex vivo (Trypsin+).
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