Table 3 Univariate and multivariate logistic regression analysis to detect risk factors for refractory ME.

From: Microaneurysms cause refractory macular edema in branch retinal vein occlusion

Univariate logistic regression analysis

Factors

OR

P value

Age

1.1

0.001**

Gender

0.7

0.465

Diabetes mellitus

2.0

0.580

Hypertension

0.9

0.900

Subtype

1.4

0.472

Initial logMAR

1.8

0.484

Initial CRT

1.0

0.086

NPA size

1.1

0.431

Microaneurysms

18

<0.001***

Collateral vessel formation

13

0.019*

Prompt (within 3 months) all treatment

1.1

0.880

Treatment

–

0.114

Retinal scatter laser photocoagulation

3.1

0.030*

Multivariate logistic regression analysis

Factors

OR (95% CI)

P Value

Microaneurysms

11 (2.3–86)

0.007**

Age

1.1 (1.0–76)

0.010*

Collateral vessels

3.1 (0.27–76)

0.385

Retinal scatter laser photocoagulation

2.6 (0.68–11)

0.166

  1. logMAR, logarithm of minimal angle of resolution. CRT, central retinal thickness. NPA, non-perfusion area. OR, odds ratio. CI, confidential interval.