Figure 4 | Scientific Reports

Figure 4

From: Conditional ablation of TGF-β signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model

Figure 4

Influence of TGF-β signaling on bladder cancer proliferation and apoptosis.

(A) Immuohistochemical analysis of bladders cancer samples from wild type (WT) or Tgfbr2 knockout (cKO) mice treated with BBN by Ki-67, active-caspase3(AcCap3) antibodies as well as stained by TUNEL assay. (B) Quantifications of Ki-67+, AcCap3+ and TUNEL positive stained cells percentage in bladder cancer samples after BBN treatment. Data represent mean ± SEM. *p < 0.05; n = 8; Student’s t-test.

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