Table 1 Characteristics of the two independent study populations.

From: Genetic Variants in the Transcriptional Regulatory Region of the ALOX5AP gene and Susceptibility to Ischemic Stroke in Chinese Populations

 

Initial study Population

Second study Population

Cases

(n = 200)

Controls

(n = 200)

Pvalue

Cases

(n = 810)

Controls

(n = 825)

Pvalue

Sex (males/females)

112/88

106/94

0.547

416/394

428/397

0.833

Age (mean ± SD, years)

57.2 ± 7.2

55.9 ± 7.0

0.090

57.7 ± 8.6

55.3 ± 7.2

0.243

Total cholesterol (mmol/L)

5.18 ± 1.09

4.54 ± 1.34

0.000*

5.22 ± 1.17

4.62 ± 1.29

0.016*

Total triglyceride (mmol/L)

1.89 ± 1.03

1.41 ± 1.01

0.000*

1.94 ± 1.31

1.35 ± 1.13

0.017*

Hypertension, (n, %)

80 (40.0)

26 (13.0)

0.000*

469 (57.9)

98 (11.9)

0.000*

Diabetes, (n, %)

32 (16.0)

9 (4.5)

0.000*

134 (16.5)

26 (3.2)

0.000*

Smokers, (n, %)

33 (16.5)

20 (10.0)

0.055

112 (13.8)

64 (7.8)

0.000*

Alcohol, (n, %)

34 (17.0)

28 (14.0)

0.407

133 (16.4)

118 (14.3)

0.235

  1. *P < 0.004 denotes statistical significance in the initial cohort.
  2. *P < 0.025 denotes statistical significance in the second cohort.
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