Table 4 Genotype and allelic distribution of rs l7222919 and rs9579646 in IS and control subjects.

From: Genetic Variants in the Transcriptional Regulatory Region of the ALOX5AP gene and Susceptibility to Ischemic Stroke in Chinese Populations

Genotype

IS subjects (n,%)

Control subjects (n,%)

P value

OR(95% CI)

rs l7222919

 TT

525 (64.8)

486 (58.9)

 

1.000

 TG

258 (31.9)

296 (35.9)

0.043

0.807 (0.656~0.993)

 GG

27 (3.3)

43 (5.2)

0.031

0.581 (0.354~0.955)

allele

 T

1308 (80.7)

1268 (76.8)

 

1.000

 G

312 (19.3)

382 (23.2)

0.007*

0.792 (0.669~0.937)

rs 9579646

 AA

185 (22.8)

179 (21.7)

 

1.000

 AG

391 (48.3)

422 (51.2)

0.386

0.896 (0.700~1.148)

 GG

234 (28.9)

224 (27.1)

0.939

1.011 (0.768~1.331)

 A

761 (47.0)

780 (47.3)

 

1.000

 G

859 (53.0)

870 (52.7)

0.865

1.012 (0.882~1.161)

  1. The P value and OR (95% CI) were adjusted for confounding factors such as age, gender, hypertension, diabetes, smoking, drinking, TC and TG. *express the adjusted P value for significance P < 0.025.
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