Figure 1: Relationship between functional activity of the MBL-MASP complex and mannose-binding lectin concentration. | Scientific Reports

Figure 1: Relationship between functional activity of the MBL-MASP complex and mannose-binding lectin concentration.

From: Polymorphisms in the Mannose-Binding Lectin Gene are Associated with Defective Mannose-Binding Lectin Functional Activity in Crohn’s Disease Patients

Figure 1

(A) Mannose-binding lectin level was determined in 30 healthy control subjects and 69 Crohn’s disease patients. There was no significant difference between the two groups. (B) No significant difference was found between the concentration of mannose-binding lectin and clinical phenotype of Crohn’s disease. Scatter plots of these data with the median line are shown. Mannose-binding lectin concentration was determined in duplicate for each sample. (C) Functional activity of the MBL-MASP complex was determined in 30 healthy controls (open dot) and 69 Crohn’s disease patients (black dot). Data are the mean ± SD of two independent experiments. (D,E) Correlation between functional activity of the MBL-MASP complex and mannose-binding lectin concentration in 30 healthy controls (P < 0.0001, R = 0.8) and 69 Crohn’s disease patients (P < 0.0001, R = 0.75). AU, Arbitrary units.

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