Figure 2: Anti-S. cerevisiae antibody levels in healthy control subjects and Crohn’s disease patients.

(A) Anti-S. cerevisiae antibody level was increased in Crohn’s disease patients when compared to healthy controls (P < 0.0001). Scatter plots of these data with the median line are shown. (B) Crohn’s disease patients with the clinical phenotype B2 had higher anti-S. cerevisiae antibody levels than those with B1 (P < 0.01) and there was a tendency for Crohn’s disease patients with B3 to have higher levels than patients with B1 (P = 0.0516). (C) Correlation between anti-S. cerevisiae antibody levels and mannose-binding lectin concentrations in Crohn’s disease patients with B3 (P < 0.015, r = −0.72). The results are expressed in arbitrary units (AU).