Figure 7
From: The role of dimensionality in neuronal network dynamics
Changes of the degree of correlated activity of 3D neuronal networks during maturation.
(a,b) Calcium transients of neurons cultured on 3D GF after 8DIV and 15 DIV respectively. (c) The mean value of IEI after 8DIV and 15DIV. (d) The correlation coefficient shows that there is a reduction in the network synchronization after 15DIV (***p < 0.001 Mann-Whitney test). (e) The correlation coefficient between pairs of neurons at different distances. While after 8DIV both near and far pairs of neurons are synchronous, at 15 DIV pairs of far neurons are less synchronous. (f) Time evolution of the correlation coefficient cc computed over a bin width of 2 minutes for 3D neuronal networks after 8DIV (yellow) and 15 DIV (green). The value of cc Correlation coefficient fluctuated similarly after 8 and 15DIV.
