Figure 4: Mice with muscle-specific ROCK1 activation develop insulin resistance. | Scientific Reports

Figure 4: Mice with muscle-specific ROCK1 activation develop insulin resistance.

From: ROCK1 reduces mitochondrial content and irisin production in muscle suppressing adipocyte browning and impairing insulin sensitivity

Figure 4

(a,b) 6 h fasting blood levels of glucose and insulin in CTL and mCaROCK1 mice at age of 6 months. (c) Glucose tolerance test (GTT) in CTL and mCaROCK1 mice. (d–f) Plasma triglycerides (D), Cholesterol (E), FFA (F) were measured in CTL and mCaROCK1 mice (mean ± SEM, n = 7, *p < 0.05 or **p < 0.01 mCaROCK1 vs. CTL).

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