Figure 8: Irisin stimulates UCP1 expression in WAT in mCaROCK1 mice. | Scientific Reports

Figure 8: Irisin stimulates UCP1 expression in WAT in mCaROCK1 mice.

From: ROCK1 reduces mitochondrial content and irisin production in muscle suppressing adipocyte browning and impairing insulin sensitivity

Figure 8

(a) Western blot revealed that UCP1 was significant increase in WAT of mCaROCK1 mice after irisin treatment (mean ± SEM, n = 5, *p < 0.05, **p < 0.01, mCaROCK1 + Irisin vs. mCaROCK1). (b) Immunohistochemistry of UCP1 in WAT of mCaROCK1 mice treated with or without irisin (DAB staining). (c) Western blot indicated that Perf-1 was significant increase in WAT of mCaROCK1 mice after irisin treatment (mean ± SEM, n = 5, *p < 0.05, **p < 0.01, mCaROCK1 + Irisin vs. mCaROCK1). (d) Immunohistochemistry of Perf-1 in WAT of mCaROCK1 mice treated with or without irisin (DAB staining).

Back to article page