Table 1 Clinicopathological information of the patients included in this study according to the TERT promoter genotype.

From: TERT promoter mutations in pancreatic endocrine tumours are rare and mainly found in tumours from patients with hereditary syndromes

 

TERT promoter genotype

wild-type

mutated

Cases studied (n, %)

51 (93%)

4 (7%)

Age (range)

54 (14–75)

44 (32–55)

Location (n, %)

Head

23 (45%)

Body

7 (14%)

2 (50%)

Tail

20 (39%)

2 (50%)

n.d.

1 (2%)

Grade (n, %)

G1

35 (69%)

2 (50%)

G2

14 (27%)

2 (50%)

G3

2 (4%)

pT stage (ENETS) (n, %)

T1

16 (31%)

T2

20 (39%)

2 (50%)

T3

12 (24%)

2 (50%)

T4

3 (6%)

pT stage (UICC/AJCC) (n, %)

T1

18 (35%)

T2

18 (35%)

1 (25%)

T3

15 (30%)

3 (75%)

T4

Lymph node metastasis (n, %)

17 out of 31 (55%)

3 (75%)

Distant metastasis (n, %)

5 (10%)1

1 (25%)2

Hereditary syndrome association

3 (75%)3

  1. n.dNot determined.
  2. 1All cases with liver metastasis, one of them with bone metastasis at the time of diagnosis.
  3. 2Liver metastasis at the time of diagnosis.
  4. 3Two MEN cases and one VHL.