Figure 3: Two chains of transmission of influenza virus by respiratory droplet or direct contact routes. | Scientific Reports

Figure 3: Two chains of transmission of influenza virus by respiratory droplet or direct contact routes.

From: Contact transmission of influenza virus between ferrets imposes a looser bottleneck than respiratory droplet transmission allowing propagation of antiviral resistance

Figure 3

Two donor ferrets one for chain 1 and one for chain 2, were infected with a total of 104 PFU of a mixture of viruses based on influenza A/England/195/2009 that differed only at two synonymous changes in PB2 gene at position 318 (A or U) and 477 (A or G) (B1 and B2). On day 1 post infection of donor, direct contact ferrets (DC1) were co-housed with donor animals and RD exposed ferrets (RD) were housed in adjacent cages that shared air with D and DC1. On day 2 post infection of donor, donor ferrets (D) were removed to separate cages and fresh contact ferrets (DC2) were introduced to the same cage as DC1.

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