Figure 2 | Scientific Reports

Figure 2

From: Heterogeneous Porphyromonas gingivalis LPS modulates immuno-inflammatory response, antioxidant defense and cytoskeletal dynamics in human gingival fibroblasts

Figure 2

(A) Gene ontology and interaction networks of proteins involved in immuno-inflammatory pathway of P. gingivalis LPS-induced secretome analysed by Ingenuity Pathways Analysis software (IPA). Red color symbol shows highly upregulated proteins (≥2 folds) compared to untreated cells. Solid lines show direct interaction and dotted lines show indirect interactions. Enzymes: ◊ kinases: ▽; transcription regulators: ⬭ and others: ⬯. (B) Gene ontology and interaction networks of proteins involved in extracellular matrix synthesis and signalling of P. gingivalis LPS-induced secretome analysed by Ingenuity Pathways Analysis software (IPA). Red color symbol shows highly upregulated proteins (≥2 folds) as compared to the untreated cells. Solid lines show direct interaction and dotted lines show indirect interactions. Enzymes: ◊; kinases: ▽; transcription regulators: ⬭ and others: ⬯.

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