Figure 3

P. gingivalis LPS induced gene expression of CTSB, CST3, PPIA and ADAM28 mRNAs in HGFs.
Cells were stimulated with P. gingivalis LPS and E. coli LPS at 1 μg/mL for 24 h. Afterwards, the harvested mRNA was subjected to real time qPCR analysis. Increased gene expression levels of CTSB (A), CST3 (B), PPIA (C) and ADAM28 (D) were noted as compared with the internal control. Each bar represents the mean ± SD of three independent experiments with three replicates. *Significant difference from the control with a P -value < 0.05.