Figure 1: The transcriptional regulatory network of gene expression in W12. | Scientific Reports

Figure 1: The transcriptional regulatory network of gene expression in W12.

From: Identification of host transcriptional networks showing concentration-dependent regulation by HPV16 E6 and E7 proteins in basal cervical squamous epithelial cells

Figure 1

The square nodes indicate central transcriptional master regulators. Those regulators for which expression levels were directly associated with HPV16 E6 protein levels are shown in green, those associated with HPV16 E7 protein levels in red and those not directly associated with E6 or E7 levels in grey. Circles indicate the downstream effector genes, with light blue indicating an overall activating regulation and pink indicating overall repression.

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