Figure 2: IL-33 enhanced IL-13 production and liver pathology in S. japonicum-infected mice only in egg-phages. | Scientific Reports

Figure 2: IL-33 enhanced IL-13 production and liver pathology in S. japonicum-infected mice only in egg-phages.

From: IL-33 Contributes to Schistosoma japonicum-induced Hepatic Pathology through Induction of M2 Macrophages

Figure 2

(a) H&E staining of liver sections (Magnification 10X). (b) Serum IL-33 was analyzed by ELISA at weeks 4, 7 and 10 post-infection. (c) Liver MNCs were purified from the liver of BALB/c mice with a mixed sex or a male-only worm infection at weeks 4, 7, 10 post-infection and activated with IL-33 (10 ng/ml) for 3 days. The supernatants were collected and IL-13 production was detected by ELISA. Data indicate mean ± SEM of 3–5 mice per group; *p < 0.05 and **p < 0.01, by the Student t test.

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