Table 1 Demographical and behavioural description of the BiliHealth study population (all subjects).

From: Features of an altered AMPK metabolic pathway in Gilbert’s Syndrome, and its role in metabolic health

Variables

Males

p-value

Females

p-value

GS

C

GS

C

Subjects [n]

40

40

1.000

20

20

1.000

Median age [yrs]^

30 (19)

31 (20)

0.965

40 (20)

40 (18)

0.766

Subjects aged </≥ 35 yrs [n/n]

24/16

24/16

1.000

9/11

9/11

1.000

Age of subjects </≥ 35 yrs^

26.5 (6.0)/45.5 (15.0)

27.0 (6.0)/45.5 (14.0)

 

29 (5)/48 (19)

29 (5)/46 (14)

 

UCB concentration [μM]°

35.3 (±10.4)

9.7 (±3.5)

0.000*

28.9 (±6.8)

8.4 (±3.1)

0.000*

UGT1A1*28 genotype/-TA repeats [% 7_7/6_7/6_6]

86.8/10.5/2.5

5.3/50/44.7

0.000*

94.7/5.3/0

5.3/45/45

0.000*

Health food consumption [times/week]°

28.6 (±9.3)

24.5 (±13.2)

0.153

32.0 (±8.0)

31.0 (±7.0)

0.611

Snack food consumption [times/week]^

10.5 (9.3)

10.0 (7.0)

0.941

9.0 (11.5)

13 (11.5)

0.876

Red meat consumption [times/week]^

3.0 (6.5)

3.0 (6.0)

0.891

0 (3)

3 (4)

0.103

Alcoholic drinks consumption [times/week]^

1 (3)

0 (2)

0.419

0 (4)

1 (3)

0.945

Overall activity [times/week]^

5.0 (3.5)

6.5 (5.5)

0.025*

6.0 (3.5)

4.0 (4.1)

0.069 T

Endurance exercise [times/week]^

2 (2)

3 (5)

0.003*

4.0 (3.0)

2.0 (2.2)

0.074 T

Resistance exercise [times/week]^

1 (2)

1 (2)

0.908

0.3 (2.0)

0.0 (1.8)

0.667

  1. (Table 1 provides a comparative (GS versus C) demographical and behavioural description of all subjects of the BiliHealth study.
  2. Based on data distribution, means° or medians^ are presented. For parametric data mean ± sd, for non-parametric distribution, medians and IQR (inter-quartile range) are given. P-values of ≤0.05* indicate significant differences; trends are reflected by p ≤ 0.1T.
  3. Insertion of additional –TA repeats in the UGT1A1*28 promoter region; 7_7: Gilbert’s syndrome, 6_7: heterozygous individuals, 6_6: wild type.
  4. Abbreviations
  5. UCB: unconjugated bilirubin; UGT1A1-genotype: UDP glucuronosyltransferase 1A1 genotype.