Table 1 Top 10 proteins unique to CN ascites tumor cells.
From: Unique proteome signature of post-chemotherapy ovarian cancer ascites-derived tumor cells
Protein Accession | Gene symbol | Protein Description | CN | CR | RSC | Gene ontology (GO) |
|---|---|---|---|---|---|---|
Q860I7 | HLA-B | MHC class I antigen | 75 | 0 | −54.5 | MHC class I protein complex; antigen processing and presentation of peptide antigen via MHC class I; immune response; integral component of membrane; peptide antigen binding; positive regulation of T cell mediated cytotoxicity |
B7ZLH8 | EVPL | EVPL protein | 52 | 0 | −38.1 | cytoskeleton |
I6NXG5 | HLA-C | MHC class I antigen | 42 | 0 | −30.9 | MHC class I protein complex; antigen processing and presentation of peptide antigen via MHC class I; immune response; peptide antigen binding; positive regulation of T cell mediated cytotoxicity |
P20592 | MX2 | Interferon-induced GTP-binding protein Mx2 | 28 | 0 | −20.9 | GTP binding; GTPase activity; cytosol; defense response to virus; mRNA transport; nuclear pore; protein transport; regulation of cell cycle; regulation of nucleocytoplasmic transport; response to interferon-alpha; type I interferon signaling pathway |
H0Y3C5 | HCK | Tyrosine-protein kinase HCK | 19 | 0 | −14.5 | NA |
B0QZ43 | ERLIN1 | Erlin-1 (Fragment) | 19 | 0 | −14.5 | ATP binding; peptidyl-tyrosine phosphorylation; protein tyrosine kinase activity |
P02549 | SPTA1 | Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin) | 16 | 0 | −12.3 | actin filament binding; actin filament capping; actin filament organization; axon guidance; calcium ion binding; cuticular plate; cytosol; hemopoiesis; intrinsic component of the cytoplasmic side of the plasma membrane; lymphocyte homeostasis; plasma membrane organization; porphyrin-containing compound biosynthetic process; positive regulation of T cell proliferation; positive regulation of protein binding; regulation of cell shape; spectrin; spectrin-associated cytoskeleton; structural constituent of cytoskeleton |
Q8IVF2 | AHNAK2 | Protein AHNAK2 | 15 | 0 | −11.6 | nucleus |
O60449 | LY75 | Lymphocyte antigen 75 (CD antigen CD205) | 14 | 0 | −10.9 | carbohydrate binding; endocytosis; immune response; inflammatory response; integral component of plasma membrane; receptor activity |
Q9ULV0 | MYO5B | Unconventional myosin-Vb | 14 | 0 | −10.9 | ATP binding; cytoplasmic vesicle membrane; microfilament motor activity; myosin complex; protein complex; protein transport; transmembrane transport; vesicle-mediated transport; water transport |
