Figure 6: Correlations of expression of cholesterol and bile acid metabolism-related genes and the OPN gene in liver tissues of gallstone patients.
From: Osteopontin Deficiency Alters Biliary Homeostasis and Protects against Gallstone Formation
Relative mRNA levels were analysed by quantitative real-time PCR. The mRNA expression of the genes was log-transformed, prior to analysis. A correlation between hepatic SHP and OPN mRNA levels (n = 21) (a) hepatic ATP8B1 and OPN mRNA levels (n = 21) (b) hepatic SR-B1 and OPN mRNA levels (n = 21) (c) and hepatic SREBP-2 and OPN mRNA levels (n = 21) (d). The correlations were performed using Pearson’s test.
