Figure 2 | Scientific Reports

Figure 2

From: Protective effect of epigallocatechin-3-gallate (EGCG) via Nrf2 pathway against oxalate-induced epithelial mesenchymal transition (EMT) of renal tubular cells

Figure 2

Induction of EMT in MDCK cells by oxalate and protective effect of EGCG against oxalate-induced EMT.

Controlled or untreated MDCK cells (A) had typical cobblestone-like morphology, whereas the cells treated with 0.5 mM sodium oxalate (B) turned into fibroblast-like morphology within 24 h. Pretreatment with 25 μM EGCG for 1 h prior to sodium oxalate treatment (C) could prevent the cells from oxalate-induced fibroblast-like morphological change. Original magnification power = 400X.

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