Table 2 Comparison of haemagglutinin inhibition test results and HA1 amino acid mutations of A(H1N1)pdm09 and A(H3N2) samples across age and gender, against the reference strains A/California/07/2009 (H1N1) and A/Victoria/361/2011 (H3N2).
From: Age-specific genetic and antigenic variations of influenza A viruses in Hong Kong, 2013–2014
Subtype | No. of samples | Dilution of antiserum in HI tests | p-value* | Genetic variations (Amino acid mutations) | p-value # | |||
|---|---|---|---|---|---|---|---|---|
160 | 320 | 640 | ≥1280 | Mean±SD | ||||
H1N1 | Age (years) | 0.42 | 0.265 | |||||
≤18 | 0 | 1 | 11 | 13 | 9.34 ± 1.79 | |||
19–64 | 0 | 1 | 12 | 8 | 10.49 ± 3.55 | |||
≥65 | 0 | 1 | 7 | 2 | 9.63 ± 1.01 | |||
Male | 0 | 0 | 15 | 10 | 0.304 | 9.50 ± 2.23 | 0.276 | |
Female | 0 | 3 | 15 | 13 | 10.00 ± 2.62 | |||
H3N2 | Age (years) | 0.798 | 0.136 | |||||
≤18 | 0 | 8 | 14 | 7 | 10.11 ± 2.59 | |||
19–64 | 1 | 5 | 7 | 4 | 9.79 ± 2.57 | |||
≥65 | 0 | 7 | 10 | 9 | 10.66 ± 2.48 | |||
Male | 0 | 14 | 15 | 12 | 0.294 | 10.13 ± 2.54 | 0.451 | |
Female | 1 | 6 | 16 | 8 | 10.38 ± 2.59 | |||
