Figure 1
(A) 1H,15N-HSQC spectrum of WT WW domain (green) superimposed to the one of its Y65C mutant (red), for which also the assignment is shown (500 MHz of 1H Larmor frequency, T = 278 K). Residues labeled with a star (*) are tentatively assigned. (B) Pictorial representation of raw values of Chemical Shift Index onto the structural model of Y65C WW domain from PQBP. Beta strand-like structures (blue) are predominant. Deviations of opposite sign are displayed in yellow. Residues for which data are not available (unassigned) are colored in gray.
