Figure 10 | Scientific Reports

Figure 10

From: Oral CoQ10 attenuates high salt-induced hypertension by restoring neurotransmitters and cytokines in the hypothalamic paraventricular nucleus

Figure 10

Effects of CoQ10 on the level of IL-1β and IL-10 in the PVN of high salt-induced hypertensive rats by Western blot.

Results showed that HS increased the level of IL-1β and decreased the level of IL-10 (P < 0.05, n = 7). 15-week of CoQ10 administration by gavage at the dose of 10 mg/kg significantly decreased the expression of IL-1β and increased the level of IL-10 compared with the NS rats (P < 0.05, n = 7). (A) Representative immunoblot of IL-1β and IL-10. (B) Densitometric analysis of protein expression of IL-1β and IL-10 in the PVN in different groups. Values are expressed as means ± SE. *P < 0.05 vs control (NS + oil or NS + CoQ10), †P < 0.05, HS + CoQ10 vs HS + oil.

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