Figure 6 | Scientific Reports

Figure 6

From: Oral CoQ10 attenuates high salt-induced hypertension by restoring neurotransmitters and cytokines in the hypothalamic paraventricular nucleus

Figure 6

Effects of CoQ10 on the levels of norepinephrine (NE), glutamate and increased GABA in the PVN of high salt-induced hypertensive rats.

These neurotransmitters were assayed by HPLC. HS rats had higher levels of NE (A) and glutamate (B) and lower levels of GABA (C) in the PVN compared with NS rats (P < 0.05, n = 7). 15-week of CoQ10 administration by gavage at the dose of 10 mg/kg significantly decreased the PVN levels of NE, glutamate and increased GABA (P < 0.05, n = 7). *P < 0.05 vs control (NS + oil or NS + CoQ10), †P < 0.05, HS + CoQ10 vs HS + oil.

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