Figure 7 | Scientific Reports

Figure 7

From: Oral CoQ10 attenuates high salt-induced hypertension by restoring neurotransmitters and cytokines in the hypothalamic paraventricular nucleus

Figure 7

Effects of CoQ10 on the levels of TH and GAD67 in the PVN of high salt-induced hypertensive rats by immunofluorescence staining.

Results showed that HS rats had higher levels of TH and lower levels of GAD67, compared with the NS rats (P < 0.05, n = 7). 15-week of CoQ10 administration by gavage at the dose of 10 mg/kg reduced TH and increased GAD67, compared with NS rats (P < 0.05, n = 7). (A) Representative immunofluorescence staining of TH and GAD67. (B) Densitometric analysis of immunofluorescent intensity of TH. (C) Densitometric analysis of immunofluorescent intensity of GAD67 in the PVN in different groups. Values are expressed as means ± SE. *P < 0.05 vs control (NS + oil or NS + CoQ10), †P < 0.05, HS + CoQ10 vs HS + oil.

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