Table 4 Correlation between intraclass correlation coefficients based on technical replicates (TR) and study duplicates (SD), by DNA source and with those from other studies.

From: Reliability of DNA methylation measures from dried blood spots and mononuclear cells using the HumanMethylation450k BeadArray

Spearman ρ

TR PBMC

TR DBS

TR PBMC adjusted for cell composition

TR DBS adjusted for cell composition

TR DBS

—

—

0.72

0.90

TR PBMC

—

0.77

0.90

0.66

SD DBS

0.84

0.80

0.79

0.71

SD PBMC

0.88

0.78

0.78

0.68

Bose, 2014b

0.80

0.72

0.73

0.63

Shvetsov, 2015b

0.57

0.55

0.60

0.54

  1. DBS: dried blood spots, PBMC: peripheral blood mononuclear cells, comp: composition Correlation between Bose and Shvetsov: ρ = 0.55.
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