Table 2 Genotype frequencies of the TSHR SNPs in the studies included in the meta-analysis.
SNP | Study | Ethnicity | Case | Control | Genotyping method | ||||
|---|---|---|---|---|---|---|---|---|---|
1* | 2* | 3* | 1* | 2* | 3* | ||||
GD rs179247A/G | Brand (2009) | Caucasian | 279 | 359 | 100 | 182 | 322 | 100 | TaqMan |
Ploski (2010) | Caucasian | 139 | 270 | 149 | 81 | 259 | 180 | TaqMan | |
Caucasian | 58 | 84 | 54 | 34 | 98 | 67 | |||
Caucasian | 879 | 1110 | 351 | 737 | 1243 | 561 | |||
Liu (2012) | Chinese | 230 | 140 | 24 | 120 | 88 | 20 | MALDI-TOF-MS | |
Inoue (2013) | Japanese | 57 | 44 | 11 | 18 | 33 | 5 | PCRRFLP | |
Bufalo (2015) | Brazilian | 117 | 138 | 24 | 92 | 154 | 50 | TaqMan | |
GD rs12101255C/T | Brand (2009) | Caucasian | 197 | 345 | 150 | 268 | 295 | 89 | TaqMan |
Ploski (2010) | Caucasian | 238 | 245 | 75 | 273 | 212 | 35 | TaqMan | |
Caucasian | 70 | 94 | 32 | 110 | 71 | 17 | |||
Caucasian | 687 | 1136 | 482 | 1046 | 1148 | 338 | |||
Liu (2012) | Chinese | 38 | 179 | 187 | 35 | 119 | 86 | MALDI-TOF-MS | |
GO rs2268458 T/C | Yin (2008) | Caucasian | 67 | 43 | 10 | 38 | 32 | 10 | PCR-RFLP |
Yin (2012) | Caucasian | 139 | 99 | 18 | 44 | 36 | 10 | PCR-RFLP | |
GO rs179247A/G | Liu (2012) | Chinese | 62 | 33 | 3 | 168 | 107 | 21 | MALDI-TOF-MS |
Jurecka (2014) | Caucasian | 80 | 126 | 77 | 91 | 148 | 77 | PCR-RFLP | |
Bufalo (2015) | Brazilian | 54 | 78 | 12 | 63 | 60 | 12 | TaqMan | |
