Table 3 Characteristics of MDD patients and controls (M ± SD).

From: Plasminogen Activator Inhibitor-1 in depression: Results from Animal and Clinical Studies

 

Controls (n = 17)

MDD (n = 17)

Before treatment

After treatment

Age (years)

54 ± 3

48 ± 12 a

—

Gender (males/females)

4/13

3/14 b

—

Education (years)

10 ± 2

13 ± 4 a

—

Body weight (kg)

67 ± 7

62 ± 15 a

—

Duration of illness (months)

—

44.5 ± 70.0

—

Episodes

—

1.5 ± 0.9

—

HDRS

2.4 ± 1.8

21.6 ± 6.3** a

4.5 ± 6.0##c

PAI-1 (pg/ml)

4.5 ± 1.6

6.2 ± 2.0* a

6.0 ± 2.2 c

  1. Notes: M: mean; SD: standard deviation; MDD: major depressive disorders; HDRS: 17-item Hamilton Depression Rating Scale.
  2. Compared with controls, *P < 0.05, **P < 0.01. Compared with “before treatment”, #P < 0.05, ##P < 0.01.
  3. aAnalysis of variance.
  4. bChi-square test.
  5. cPaired-samples t-test.
Back to article page