Figure 2
Colour photographs show the shadow of LDH tablets (black arrows) between muscle layers of the both sides of the abdominal wall, anatomically separated by xiphoidal appendix, while the grey pictures show the pattern of the microcirculation over the tablets, captured by SDF videomicroscopy “in vivo”, both at 7th (A) and 28th (B) P.O. days. The coloured images were taken from the peritoneal side, following a large U-shape incision of the abdominal wall and with aid of the transillumination. At both time periods, no signs of tissue inflammation were seen around tablets and the microcirculatory network was also of normal aspect, showing a continuous blood flow without capillaries hemorrhage or thrombosis. SDF images size are of 1 mm2/frame containing muscle microvessels. Sham surgery: surgical procedures mimicking the tablet implantation procedure (C). Superior - Normal macroscopic aspect of the rat abdominal wall of the naïve animal, viewed from peritoneal side; circle indicates the usual site for the tablet implantation. Inferior - SDF images of the abdominal wall of the control group, showing normal pattern of microcirculatory at 7th and 28th P.O. days.
