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Figure 1

From: Warfarin and coumarin-like Murraya paniculata extract down-regulate EpCAM-mediated cell adhesion: individual components versus mixture for studying botanical metastatic chemopreventives

Figure 1

Schematic of bioactivity-guided fast screen for cancer metastatic chemopreventive materials from raw extracts of Murraya paniculata.

Procedures of extracting active components from the plant roots: the roots were collected, dried and powdered. The raw powder was refluxed with 80% acid ethanol and the concentrated residual was extracted with ethyl acetate. The extract was subjected to HPLC semi-preparation column separation, which resulted in five coumarin-like components in amorphous powders after rotary evaporation and lyophilization. The powders were tested for their pharmacological activities.

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